Assassins Creed Odyssey Atlantis Artifacts Locations And Collection Guide

Unsealing the gates to the lost city of Atlantis is one of the most pivotal questlines in Assassin's Creed Odyssey. To accomplish this monumental task, Kassandra or Alexios must travel across ancient Greece to recover four powerful Isu artifacts guarded by legendary mythological beasts. Locating these items requires completing specific quest chains, solving intricate riddles, and defeating formidable bosses in battle.
Starting the Atlantis Artifact Questline
Before hunting down the artifacts, players must first initiate the main storyline quest titled A Family's Legacy on the volcanic island of Thera. Following the clues leads to the discovery of the gateway to Atlantis and an encounter with Pythagoras. He tasks the Eagle Bearer with securing four key artifacts to seal the gateway and protect the world from Isu power.
Preparing for these missions requires reaching a high character level and gearing up with strong fire or poison builds. Each artifact is tied to a distinct region of the map, demanding both tactical preparation and storyline progress. Navigating these challenges effectively ensures a smooth path toward unlocking the game's secret endings.
Defeating the Minotaur and Sphinx
The Minotaur's artifact is hidden deep within the Labyrinth of Souls located beneath the Messara region. Players must complete the Myths and Minotaurs questline in the Pephka and Messara regions to earn access to the maze. Once inside, navigating the winding corridors leads to a heavy boss battle against the heavy-hitting beast.
In contrast, obtaining the Sphinx's artifact on the island of Boeotia relies on intellect rather than raw strength. After completing the Lore of the Sphinx quest, players engage in a high-stakes riddle contest during the night. Answering the three questions correctly bypasses combat entirely, rewarding the player with the second artifact upon completion.
Overcoming the Cyclops and Medusa
The Cyclops guards his artifact on the island of Kythera within the Forgotten Isle cave network. Initiating the quest A God Among Men unlocks the path to face Brontes the Thunderer in his arena. Striking his exposed glowing eye interrupts his deadliest attacks and makes the encounter far more manageable.
The final artifact requires defeating Medusa inside the Petrified Temple on the island of Lesbos. Unlocking her lair involves completing the Shadow of Serpents questline across the island's petrified forest. Medusa presents the most challenging boss fight in the base game, requiring precise dodges behind stone pillars to avoid her freezing gaze while clearing out her summoned stone warriors.
Sealing Atlantis and Final Rewards
Once all four ancient artifacts are collected, return to the gateway under Thera to present them to Pythagoras. Placing each artifact into its corresponding pedestal triggers key story revelations regarding the Isu civilization and modern-day narrative. Completing the sequence permanently seals the city of Atlantis and unlocks powerful legendary weapons for your inventory.
Finishing this main questline also sets up the narrative foundation for the Fate of Atlantis downloadable content expansions. Players walk away with massive experience gains, top-tier equipment, and a deeper understanding of ancient Greek mythology. Managing your travel route across the islands ensures an efficient collection journey for any completionist.